Et(cre/ERT2)25175Rdav
Transgene Detail

Summary

• Symbol: Et(cre/ERT2)25175Rdav
• Name: enhancer trap 25175, Ron Davis
• MGI ID: MGI:5009328
• Synonyms: Pak7-Cre-ERT2-bGHpA line #25175
• Transgene: Et(cre/ERT2)25175Rdav Location: unknown
• Alliance: Et(cre/ERT2)25175Rdav page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Et(cre/ERT2)25175Rdav expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Et(cre/ERT2)25175Rdav (MGI:5009323)

• Mutation details: The Pak7-Cre-ERT2-bGHpA transgene was designed with a mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) minimal promoter (-77 to +277), a rabbit beta globin intron (650 bp), a CreERT2 fusion gene (Cre-ERT2), and a bovine growth hormone polyA signal. This transgene was injected into C57BL/6J mouse embryos. To establish founder line 25175, founder mice (F0) were bred to B6.R26-lacZ mutant mice (Gt(ROSA)26Sortm1Sor mutant mice backcrossed to C57BL/6N or C57BL/6J for at least 10 generations. CreERT2-positive::lacZ-positive transgenic mice (F1) were bred to C57BL/6 mice. (J:150856)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Et(cre/ERT2)25175Rdav (mouse) Summary of all recombinase alleles driven by Et(cre/ERT2)25175Rdav. Alliance mouse Et(cre/ERT2)25175Rdav gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009
• All: 1 reference(s)