Syce3^tm1Rben
Targeted Allele Detail

Summary

• Symbol: Syce3^tm1Rben
• Name: synaptonemal complex central element protein 3; targeted mutation 1, Ricardo Benavente
• MGI ID: MGI:5009455
• Gene: Syce3 Location: Chr15:89274377-89294706 bp, - strand Genetic Position: Chr15, 44.87 cM
• Alliance: Syce3^tm1Rben page

Disruption of meiosis in Syce3^tm1Rben/Syce3^tm1Rben mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172714
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exons 2 and 3, the coding exons, were replaced with a neo cassette via homologous recombination. (J:172714)

Generation of the Syce3^tm1Rben allele

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Syce3 Mutation: 5 strains or lines available

Notes

ES cell line = R1/E (J:172714)

References

• Original: J:172714 Schramm S, et al., A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility. PLoS Genet. 2011 May;7(5):e1002088
• All: 3 reference(s)