Tg(Nes-cre/ERT2)1Adra
Transgene Detail

Summary

• Symbol: Tg(Nes-cre/ERT2)1Adra
• Name: transgene insertion 1, Alex Dranovsky
• MGI ID: MGI:5009457
• Synonyms: line H, Nes-CreER^T2, Nestin-CreERT2
• Transgene: Tg(Nes-cre/ERT2)1Adra Location: unknown
• Alliance: Tg(Nes-cre/ERT2)1Adra page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Nes-cre/ERT2)1Adra expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Nes (25491)

  Nes	(MGI:101784)

• Mutation details: The cre/ERT2 sequence was cloned into a plasmid containing a 5.3 kb fragment of the rat Nestin gene promoter. Transgenic mice were generated by pronuclear injection of the purified construct into fertilized embryos. (J:171377, J:173005)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (rat) Summary of all recombinase alleles driven by Nes. Comparative matrix view of recombinase activities Alliance rat Nes gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:171377 Sahay A, et al., Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature. 2011 Apr 28;472(7344):466-70
• All: 14 reference(s)