Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp
Transgene Detail

Summary

• Symbol: Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp
• Name: transgene insertion, David M Spencer
• MGI ID: MGI:5009681
• Synonyms: JOCK-2, JOCK2
• Transgene: Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp Location: unknown
• Alliance: Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgfr2 (MGI:95523)

• Mutation details: The promoter drives prostate epithelium-specific expression of the intracellular domain with a 5' myristolation site and, at the 3', two tandem AP20187 drug binding domains for chemically induced dimerization and an HA tag. Two lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:87092)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:87092 Freeman KW, et al., Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res. 2003 Dec 1;63(23):8256-63
• All: 1 reference(s)