Tg(Acp5-Adam8)#Rood
Transgene Detail

Summary

• Symbol: Tg(Acp5-Adam8)#Rood
• Name: transgene insertion, G David Roodman
• MGI ID: MGI:5009707
• Synonyms: TRAP-ADAM8
• Transgene: Tg(Acp5-Adam8)#Rood Location: unknown
• Alliance: Tg(Acp5-Adam8)#Rood page

Transgene origin

• Strain of Origin: (C57BL/6 x BALB/c)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Acp5-Adam8)#Rood expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Adam8 (MGI:107825)

• Mutation details: The mouse promoter drives osteoclast-specific expression of the mouse cDNA. Two lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:172936)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172936 Ishizuka H, et al., ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivo. J Bone Miner Res. 2011 Jan;26(1):169-81
• All: 1 reference(s)