Gt(ROSA)26Sor^{tm2(Rnf187)Jhai}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(Rnf187)Jhai}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Jody Haigh
• MGI ID: MGI:5013401
• Synonyms: R26^RACO-1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(Rnf187)Jhai} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173145
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(Rnf187)Jhai} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  RNF187 (149603)

  Rnf187

  (MGI:1914224)

• Mutation details: A floxed neo/stop cassette and a cDNA for Rnf187 with an IRES-EGFP was inserted into the locus. (J:173145)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:173145 Davies CC, et al., Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation. Nat Cell Biol. 2010 Oct;12(10):963-72
• All: 1 reference(s)