Hormad1^tm1.2Atot
Targeted Allele Detail

Summary

• Symbol: Hormad1^tm1.2Atot
• Name: HORMA domain containing 1; targeted mutation 1.2, Attila Toth
• MGI ID: MGI:5013481
• Synonyms: Hormad1^deletion
• Gene: Hormad1 Location: Chr3:95466988-95494982 bp, + strand Genetic Position: Chr3, 40.74 cM, cytoband F2
• Alliance: Hormad1^tm1.2Atot page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173089
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination of Hormad1^tm1.2Atot removed exon 4. The absence of protein expression was confirmed by western blot analysis on testis extract. (J:173089)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hormad1 Mutation: 32 strains or lines available

References

• Original: J:173089 Daniel K, et al., Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610
• All: 5 reference(s)