Car6^tm1Pwp
Targeted Allele Detail

Summary

• Symbol: Car6^tm1Pwp
• Name: carbonic anhydrase 6; targeted mutation 1, Pei-wen Pan
• MGI ID: MGI:5013650
• Gene: Car6 Location: Chr4:150271472-150285592 bp, - strand Genetic Position: Chr4, 81.12 cM
• Alliance: Car6^tm1Pwp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172854
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 and 4 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on submandibular and parotid gland extracts. (J:172854)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Car6 Mutation: 17 strains or lines available

References

• Original: J:172854 Pan PW, et al., Gene expression profiling in the submandibular gland, stomach, and duodenum of CAVI-deficient mice. Transgenic Res. 2011 Jun;20(3):675-98
• All: 3 reference(s)