Ffar3^tm1Gzt
Targeted Allele Detail

Summary

• Symbol: Ffar3^tm1Gzt
• Name: free fatty acid receptor 3; targeted mutation 1, Gozoh Tsujimoto
• MGI ID: MGI:5013799
• Synonyms: Gpr41^-
• Gene: Ffar3 Location: Chr7:30553755-30555603 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar3^tm1Gzt page

Reduced sympathetic nerve activity in Ffar3^tm1Gzt/Ffar3^tm1Gzt mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172798
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion The coding region is replaced with a neo cassette. (J:172798)

Targeting vector for construction of Ffar3^tm1Gzt mice

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar3 Mutation: 18 strains or lines available

References

• Original: J:172798 Kimura I, et al., Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41). Proc Natl Acad Sci U S A. 2011 May 10;108(19):8030-5
• All: 5 reference(s)