Tg(DCX-cre/ERT2)1Mull
Transgene Detail

Summary

• Symbol: Tg(DCX-cre/ERT2)1Mull
• Name: transgene insertion 1, Ulrich Mueller
• MGI ID: MGI:5014069
• Transgene: Tg(DCX-cre/ERT2)1Mull Location: unknown
• Alliance: Tg(DCX-cre/ERT2)1Mull page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(DCX-cre/ERT2)1Mull expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  DCX (1641)

  Dcx	(MGI:1277171)

• Mutation details: A transgene was designed with the human doublecortin (DCX) promoter/enhancer regions upstream of a CreERT2 fusion gene (Cre-ERT2; Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand-binding domain). This transgene was microinjected into the pronucleus of C57BL/6J zygotes. Transgenic mice from a single founder line were bred to C57BL/6J mice. (J:151755)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	DCX (human) Summary of all recombinase alleles driven by DCX. Comparative matrix view of recombinase activities Alliance human DCX gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009
• All: 10 reference(s)