Cux2^{tm1.1(cre)Mull}
Targeted Allele Detail

Summary

• Symbol: Cux2^{tm1.1(cre)Mull}
• Name: cut-like homeobox 2; targeted mutation 1.1, Ulrich Mueller
• MGI ID: MGI:5014209
• Synonyms: Cux2-IRES-Cre
• Gene: Cux2 Location: Chr5:121996025-122188522 bp, - strand Genetic Position: Chr5, 62.02 cM
• Alliance: Cux2^{tm1.1(cre)Mull} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151755
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a
• Project Collection: Neuroscience Blueprint cre

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Cux2^{tm1.1(cre)Mull} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cux2 (MGI:107321)

• Mutation details: A targeting vector was designed to insert an internal ribosomal entry site, nuclear-localized Cre recombinase gene, and polyA signal (IRES-Cre-pA) followed by an FRT-flanked PGK-Neo cassette into the 3' untranslated region of the cut-like homeobox 2 (Cux2) locus. Flp-mediated recombination removed the FRT-flanked PGK-Neo cassette. (J:151755)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cux2 (mouse) Summary of all recombinase alleles driven by Cux2. Comparative matrix view of recombinase activities Alliance mouse Cux2 gene page

Expression

In Mice Carrying this Mutation:

68 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cux2 Mutation: 43 strains or lines available

References

• Original: J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009
• All: 14 reference(s)