Dock2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dock2^m1Btlr
• Name: dedicator of cyto-kinesis 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5014755
• Synonyms: Dock2^frazz
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at position 34148572 (Genbank genomic region NC_000077). The mutation is located within the donor splice site of intron 21 from the ATG exon, two nucleotides from the previous exon. (J:173592) Additional incidental mutations were detected in sequencing for the causative mutation, Dock2^m1Btlr, and may be present in stocks carrying this mutation.

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 143 strains or lines available

References

• Original: J:173592 Beutler B, Direct Data Submission 2011/07/15. MGI Direct Data Submission. 2011
• All: 2 reference(s)