Slc2a3^tm1Stua
Targeted Allele Detail

Summary

• Symbol: Slc2a3^tm1Stua
• Name: solute carrier family 2 (facilitated glucose transporter), member 3; targeted mutation 1, Charles A Stuart
• MGI ID: MGI:5014841
• Gene: Slc2a3 Location: Chr6:122704768-122778599 bp, - strand Genetic Position: Chr6, 57.82 cM
• Alliance: Slc2a3^tm1Stua page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172531
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by a 52% reduction in protein levels in a western blot brain lysate from heterozygous mice. (J:172531)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a3 Mutation: 43 strains or lines available

References

• Original: J:172531 Stuart CA, et al., Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake. Brain Res. 2011 Apr 12;1384:15-22
• All: 1 reference(s)