Tg(Slc32a1-icre/ERT2)3Gloss
Transgene Detail

Summary

• Symbol: Tg(Slc32a1-icre/ERT2)3Gloss
• Name: transgene insertion 3, Bernd Gloss
• MGI ID: MGI:5049903
• Synonyms: VGAT-iCreER
• Transgene: Tg(Slc32a1-icre/ERT2)3Gloss Location: unknown
• Alliance: Tg(Slc32a1-icre/ERT2)3Gloss page

Transgene origin

• Strain of Origin: C57BL/6NTac

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Slc32a1-icre/ERT2)3Gloss expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc32a1 (MGI:1194488)

• Mutation details: The mouse bacterial artificial chromosome (BAC) RP23-392P11 containing the Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, gene, was modified by insertion of sequence encoding iCreER at the Slc32a1 translation initiation ATG, and addition of a Kozak sequence upstream of the ATG. This BAC also contains these additional genes Adig (adipogenin), Arhgap40 (Rho GTPase activating protein 40), AK134637, BC072662, and Actr5 (P5 actin-related protein 5 homolog (yeast)). The modified BAC was used to generate the VGAT-iCreER transgene, which was microinjected into C57BL/6NTac fertilized eggs. Founder line 3 was subsequently established. (J:173675)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc32a1 (mouse) Summary of all recombinase alleles driven by Slc32a1. Alliance mouse Slc32a1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:173675 Gloss B, Generation of an inducible Slc32a1 cre transgene. MGI Direct Data Submission. 2001
• All: 2 reference(s)