Adh5tm1.1Llli
Targeted Allele Detail
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Symbol: |
Adh5tm1.1Llli |
Name: |
alcohol dehydrogenase 5 (class III), chi polypeptide; targeted mutation 1.1, Limin Liu |
MGI ID: |
MGI:5049924 |
Synonyms: |
GSNORf |
Gene: |
Adh5 Location: Chr3:138148854-138161260 bp, + strand Genetic Position: Chr3, 64.26 cM
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Alliance: |
Adh5tm1.1Llli page
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Germline Transmission: |
Earliest citation of germline transmission:
J:173666
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 5. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exons 5 and 6 floxed.
(J:173666)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Adh5 Mutation: |
28 strains or lines available
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Original: |
J:173666 Wei W, et al., Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis. 2011 Jul;32(7):973-7 |
All: |
2 reference(s) |
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