Rr14tm1.1Bulg
Targeted Allele Detail
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Symbol: |
Rr14tm1.1Bulg |
Name: |
regulatory region 14; targeted mutation 1.1, Michael Bulger |
MGI ID: |
MGI:5049943 |
Synonyms: |
HS-E1 deletion |
Gene: |
Rr14 Location: unknown Genetic Position: Chr7, Syntenic
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Alliance: |
Rr14tm1.1Bulg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:173283
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
Mutation: |
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Intergenic deletion
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Mutation details: Homologous recombination replaced a segment of genomic DNA located between Hbb-bh0 and Hbb-bh1 with a loxP site flanked neomycin resistance gene cassette. The segment of DNA replaced extended from 7500 bp downstream of the epsilon y-globin transcription start site to 8231 bp downstream (731 bp). The selectable marker was subsequently removed by crossing to Tg(CMV-cre)1Cgn transgenic mice.
(J:173283)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr14 Mutation: |
0 strains or lines available
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Original: |
J:173283 Fromm G, et al., An embryonic stage-specific enhancer within the murine beta-globin locus mediates domain-wide histone hyperacetylation. Blood. 2011 May 12;117(19):5207-14 |
All: |
1 reference(s) |
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