Kdm4d^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Kdm4d^tm1Zuk
• Name: lysine (K)-specific demethylase 4D; targeted mutation 1, Martin M Matzuk
• MGI ID: MGI:5051955
• Gene: Kdm4d Location: Chr9:14373844-14411778 bp, - strand Genetic Position: Chr9, 4.05 cM
• Alliance: Kdm4d^tm1Zuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173703
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame in exon 2 was replaced with a neo cassette. RT-PCR confirmed the absence of transcripts containing the open reading frame. (J:173703)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm4d Mutation: 33 strains or lines available

References

• Original: J:173703 Iwamori N, et al., The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility. Biol Reprod. 2011 Jun;84(6):1225-34
• All: 1 reference(s)