Sfrp4^tm1.1Blan
Targeted Allele Detail

Summary

• Symbol: Sfrp4^tm1.1Blan
• Name: secreted frizzled-related protein 4; targeted mutation 1.1, Beate Lanske
• MGI ID: MGI:5052054
• Gene: Sfrp4 Location: Chr13:19807345-19816995 bp, + strand Genetic Position: Chr13, 6.99 cM
• Alliance: Sfrp4^tm1.1Blan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173962
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted 5' of the translation initiation site in exon 1 and a floxed neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1. (J:173962)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp4 Mutation: 18 strains or lines available

References

• Original: J:173962 Christov M, et al., Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. Endocrinology. 2011 May;152(5):2031-6
• All: 4 reference(s)