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Sart3tm1.1Hbro
Targeted Allele Detail
Summary
Symbol: Sart3tm1.1Hbro
Name: squamous cell carcinoma antigen recognized by T cells 3; targeted mutation 1.1, Hal E Broxmeyer
MGI ID: MGI:5052106
Gene: Sart3  Location: Chr5:113880505-113910461 bp, - strand  Genetic Position: Chr5, 55.55 cM
Alliance: Sart3tm1.1Hbro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173259
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 13. An additional loxP site was inserted downstream of exon 18. Cre-mediated recombination removed the neo cassette and left exons 13 through 18 floxed. (J:173259)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sart3 Mutation:  46 strains or lines available
References
Original:  J:173259 Liu Y, et al., TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC. Blood. 2011 May 26;117(21):5643-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory