St6galnac2^tm1.1Cfg
Targeted Allele Detail

Summary

• Symbol: St6galnac2^tm1.1Cfg
• Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; targeted mutation 1.1, Consortium for Functional Glycomics
• MGI ID: MGI:5052157
• Gene: St6galnac2 Location: Chr11:116567529-116586608 bp, - strand Genetic Position: Chr11, 81.49 cM, cytoband E2
• Alliance: St6galnac2^tm1.1Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Three LoxP sites were inserted to flank exon 3 and a PGKneo cassette. Cre-mediated recombination removed exon 3 and the neo cassette. (J:94077)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any St6galnac2 Mutation: 30 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)