Lcn2^tm1Mrgr
Targeted Allele Detail

Summary

• Symbol: Lcn2^tm1Mrgr
• Name: lipocalin 2; targeted mutation 1, Michael R Green
• MGI ID: MGI:5052158
• Synonyms: 24p3^-
• Gene: Lcn2 Location: Chr2:32274649-32277751 bp, - strand Genetic Position: Chr2, 22.09 cM, cytoband A3
• Alliance: Lcn2^tm1Mrgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173490
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exons 1 through 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on urine samples. (J:173490)

Generation of the Lcn2^tm1Mrgr/Lcn2^tm1Mrgr null mice

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcn2 Mutation: 29 strains or lines available

References

• Original: J:173490 Liu Z, et al., Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J Biol Chem. 2011 Jun 10;286(23):20606-14
• All: 3 reference(s)