Mgat5b^tm1.1Cfg
Targeted Allele Detail

Summary

• Symbol: Mgat5b^tm1.1Cfg
• Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B; targeted mutation 1.1, Consortium for Functional Glycomics
• MGI ID: MGI:5052168
• Gene: Mgat5b Location: Chr11:116809689-116877774 bp, + strand Genetic Position: Chr11, 81.49 cM
• Alliance: Mgat5b^tm1.1Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: CMTI-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP-flanked PGKneo cassette site was inserted upstream of exon 2 and a third loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette. Exon 2 was subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. (J:94077)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgat5b Mutation: 66 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)