Siglech^tm1.1Cfg
Targeted Allele Detail

Summary

• Symbol: Siglech^tm1.1Cfg
• Name: sialic acid binding Ig-like lectin H; targeted mutation 1, Consortium for Functional Glycomics
• MGI ID: MGI:5052173
• Gene: Siglech Location: Chr7:55417926-55428673 bp, + strand Genetic Position: Chr7, 33.42 cM
• Alliance: Siglech^tm1.1Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a second loxP site followed by an FRT-flanked PGKneo cassette site were inserted downstream of exon 2. The selection cassette and exons 1 and 2 were subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. (J:94077)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Siglech Mutation: 24 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 4 reference(s)