Kiss1r^{tm1.1(cre)Uboe}
Targeted Allele Detail

Summary

• Symbol: Kiss1r^{tm1.1(cre)Uboe}
• Name: KISS1 receptor; targeted mutation 1.1, Ulrich Boehm
• MGI ID: MGI:5052305
• Synonyms: GPIC, Gpr54^neo-
• Gene: Kiss1r Location: Chr10:79752805-79758107 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Kiss1r^{tm1.1(cre)Uboe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173936
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Kiss1r^{tm1.1(cre)Uboe} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Kiss1r (MGI:2148793)

• Mutation details: An IRES-cre with an FRT-flanked neo cassette was inserted into exon 5 downstream of the coding region. Flp-mediated recombination removed the neo cassette. (J:173936)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kiss1r (mouse) Summary of all recombinase alleles driven by Kiss1r. Alliance mouse Kiss1r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kiss1r Mutation: 21 strains or lines available

References

• Original: J:173936 Mayer C, et al., Female reproductive maturation in the absence of kisspeptin/GPR54 signaling. Nat Neurosci. 2011 Jun;14(6):704-10
• All: 3 reference(s)