Hrh3^tm1.1Jhwa
Targeted Allele Detail

Summary

• Symbol: Hrh3^tm1.1Jhwa
• Name: histamine receptor H3; targeted mutation 1.1, Joyce J Hwa
• MGI ID: MGI:5052375
• Gene: Hrh3 Location: Chr2:179741258-179746264 bp, - strand Genetic Position: Chr2, 102.62 cM
• Alliance: Hrh3^tm1.1Jhwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174155
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding and non-coding sequences were deleted. Flp-mediated recombination removed the neo cassette.

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hrh3 Mutation: 20 strains or lines available

References

• Original: J:174155 Henry MB, et al., Antidiabetic properties of the histamine H3 receptor protean agonist proxyfan. Endocrinology. 2011 Mar;152(3):828-35
• All: 1 reference(s)