Twsg1^tm1Aptr
Targeted Allele Detail

Summary

• Symbol: Twsg1^tm1Aptr
• Name: twisted gastrulation BMP signaling modulator 1; targeted mutation 1, Anna Petryk
• MGI ID: MGI:5056109
• Synonyms: Twsg1^flox
• Gene: Twsg1 Location: Chr17:66230060-66258198 bp, - strand Genetic Position: Chr17, 35.26 cM
• Alliance: Twsg1^tm1Aptr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173627
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 4 (third coding exon) was flanked with loxP sites. (J:173627)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Twsg1 Mutation: 20 strains or lines available

References

• Original: J:173627 Billington CJ Jr, et al., The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice. Dev Biol. 2011 Jul 1;355(1):21-31
• All: 2 reference(s)