Ttk^tm1Katj
Targeted Allele Detail

Summary

• Symbol: Ttk^tm1Katj
• Name: Ttk protein kinase; targeted mutation 1, Katja Wassmann
• MGI ID: MGI:5056148
• Synonyms: Mps1^F
• Gene: Ttk Location: Chr9:83716742-83754442 bp, + strand Genetic Position: Chr9, 45.61 cM
• Alliance: Ttk^tm1Katj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173618
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 3 and 4, which encode the kinetochore-binding domain, were floxed. (J:173618, J:216365)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttk Mutation: 53 strains or lines available

References

• Original: J:173618 Hached K, et al., Mps1 at kinetochores is essential for female mouse meiosis I. Development. 2011 Jun;138(11):2261-71
• All: 5 reference(s)