Tg(tetO-MAP2K1)#Ahsa
Transgene Detail
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| Symbol: |
Tg(tetO-MAP2K1)#Ahsa |
| Name: |
transgene insertion, AH Sawalha |
| MGI ID: |
MGI:5056483 |
| Synonyms: |
TRE2-MEK |
| Transgene: |
Tg(tetO-MAP2K1)#Ahsa Location: unknown
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| Alliance: |
Tg(tetO-MAP2K1)#Ahsa page
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| Transgene Type: |
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Transgenic (Dominant negative, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: A dominant-negative mutation of a human cDNA encoding S218A, S222A, and K97A amino acid residue substitutions was placed under the control of TRE2 (tetO) regulatory elements. The purified construct was then injected into nuclei of one-celled embryos.
(J:174339, J:174340)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:174339 Sawalha AH, et al., Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun. 2008 Jun;9(4):368-78 |
| All: |
2 reference(s) |
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Analysis Tools
