Atad1^tm1.1Vdaw
Targeted Allele Detail

Summary

• Symbol: Atad1^tm1.1Vdaw
• Name: ATPase family, AAA domain containing 1; targeted mutation 1.1, Valina Dawson
• MGI ID: MGI:5085323
• Gene: Atad1 Location: Chr19:32649958-32717187 bp, - strand Genetic Position: Chr19, 27.55 cM, cytoband C3
• Alliance: Atad1^tm1.1Vdaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173768
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exons 5 and 6 and the neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:173768)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atad1 Mutation: 38 strains or lines available

References

• Original: J:173768 Zhang J, et al., The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell. 2011 Apr 15;145(2):284-99
• All: 7 reference(s)