Gsdma3^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gsdma3^{tm1(KOMP)Vlcg}
• Name: gasdermin A3; targeted mutation 1, Velocigene
• MGI ID: MGI:5085494
• Gene: Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
• Alliance: Gsdma3^{tm1(KOMP)Vlcg} page
• IMPC: Gsdma3 gene page

Mutation origin

• Mutant Cell Lines: 10224A-A4, 10224A-A9, 10224A-B12, 10224A-C8, 10224A-H4
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 27951bp between positions 98528917-98556867 of Chromosome 11 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Gsdma3 Mutation: 26 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)