Apbb1ip^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Apbb1ip^{tm1(KOMP)Vlcg}
• Name: amyloid beta precursor protein binding family B member 1 interacting protein; targeted mutation 1, Velocigene
• MGI ID: MGI:5085540
• Synonyms: Apbb1ip^-, RIAM-null
• Gene: Apbb1ip Location: Chr2:22664106-22765665 bp, + strand Genetic Position: Chr2, 15.15 cM, cytoband A3
• Alliance: Apbb1ip^{tm1(KOMP)Vlcg} page
• IMPC: Apbb1ip gene page

Mutation origin

• Mutant Cell Lines: 16066A-D4, 16066A-D5
• Germline Transmission: Earliest citation of germline transmission: J:220786
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 14805bp between positions 22709620-22724424 of Chromosome 2 (Build GRCm39) removing exons 3 to 6. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Apbb1ip Mutation: 43 strains or lines available

Notes

Cell line 16066A-D5 was successfully used to make chimeric mice. Germline transmission was accomplished. J:220786

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)