Nlrp10^tm1Seis
Targeted Allele Detail

Summary

• Symbol: Nlrp10^tm1Seis
• Name: NLR family, pyrin domain containing 10; targeted mutation 1, Stephanie C Eisenbarth
• MGI ID: MGI:5085851
• Gene: Nlrp10 Location: Chr7:108521060-108529365 bp, - strand Genetic Position: Chr7, 57.21 cM, cytoband E3
• Alliance: Nlrp10^tm1Seis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173245
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 including the translation start site were replaced with a floxed neo cassette via homologous recombination. (J:183989)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp10 Mutation: 39 strains or lines available

References

• Original: J:173245 Elinav E, et al., NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis. Cell. 2011 May 27;145(5):745-57
• All: 5 reference(s)