Emc10^{Gt(OST181617)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Emc10^{Gt(OST181617)Lex}
• Name: ER membrane protein complex subunit 10; gene trap OST181617, Lexicon Genetics
• MGI ID: MGI:5085894
• Synonyms: 2310044H10Rik^{Gt(OST181617)Lex}, Mirta22^-
• Gene: Emc10 Location: Chr7:44139361-44145953 bp, - strand Genetic Position: Chr7, 28.83 cM
• Alliance: Emc10^{Gt(OST181617)Lex} page

Mutation origin

• Mutant Cell Line: OST181617
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Emc10 (RIKEN cDNA 2310044H10) gene consists of 7 exons. Retroviral insertion disrupted the gene in the intron between coding exons 1 and 2 (NCBI accession NM_197991.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:94077)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Emc10 Mutation: 19 strains or lines available

Notes

This Lexicon Genetics gene trap mutation was generated in either Lex-1 or Lex-2 (129S5/SvEvBrd) parental ES cell line. The specific ES cell line in which this mutation was made is not specified.

References

• Original: J:171883 Lexicon Genetics, Inc, MGI download of Lexicon knockout data. Database Download. 2011
• All: 6 reference(s)