Sec23ip^tm1.1Katn
Targeted Allele Detail

Summary

• Symbol: Sec23ip^tm1.1Katn
• Name: Sec23 interacting protein; targeted mutation 1.1, Katsuko Tani
• MGI ID: MGI:5085903
• Synonyms: p125^-
• Gene: Sec23ip Location: Chr7:128346667-128386560 bp, + strand Genetic Position: Chr7, 70.51 cM
• Alliance: Sec23ip^tm1.1Katn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174226
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a pgk-neo cassette and loxP site were inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1 and a the neo cassette. (J:174226)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sec23ip Mutation: 65 strains or lines available

References

• Original: J:174226 Arimitsu N, et al., p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis. FEBS Lett. 2011 Jul 21;585(14):2171-6
• All: 1 reference(s)