Kcnn2^bc-7J
Spontaneous Allele Detail

Summary

• Symbol: Kcnn2^bc-7J
• Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; bouncy 7 Jackson
• MGI ID: MGI:5140330
• Gene: Kcnn2 Location: Chr18:45401927-45818950 bp, + strand Genetic Position: Chr18, 24.34 cM, cytoband C
• Alliance: Kcnn2^bc-7J page

Mutation origin

• Strain of Origin: B6.129P2-Apoe^tm1Unc/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous A-to-T transition at chromosome 18 position 45,685,419 (GRCm38) causes a nonsense mutation in the fourth exon changing amino acid 528/793/803 from arginine to a stop codon (NP_536713:p.R528*, ENSMUSP00000067884:p.R793*, NP_001299834:p.R803*). (J:207676, J:222308)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnn2 Mutation: 43 strains or lines available

References

• Original: J:207676 Dionne LA, et al., The bouncy alleles are mutations in the Kcnn2 gene. MGI Direct Data Submission. 2014
• All: 2 reference(s)