Tbx1^tm7.1Bld
Targeted Allele Detail

Summary

• Symbol: Tbx1^tm7.1Bld
• Name: T-box 1; targeted mutation 7.1, Antonio Baldini
• MGI ID: MGI:5140345
• Synonyms: Tbx1^deltaFox
• Gene: Tbx1 Location: Chr16:18399729-18409412 bp, - strand Genetic Position: Chr16, Syntenic
• Alliance: Tbx1^tm7.1Bld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166754
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: The Fox binding site #1 was replaced with a floxed Hprt selection cassette. Cre-mediated recombination removed the selection cassette. (J:166754)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx1 Mutation: 36 strains or lines available

References

• Original: J:166754 Zhang Z, et al., Manipulation of endogenous regulatory elements and transgenic analyses of the Tbx1 gene. Mamm Genome. 2010 Dec;21(11-12):556-64
• All: 1 reference(s)