Tg(Dct-lacZ)#Ove
Transgene Detail
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| Symbol: |
Tg(Dct-lacZ)#Ove |
| Name: |
transgene insertion, Paul A Overbeek |
| MGI ID: |
MGI:5140350 |
| Synonyms: |
DctlacZ, TRP2-lacZ |
| Transgene: |
Tg(Dct-lacZ)#Ove Location: unknown
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| Alliance: |
Tg(Dct-lacZ)#Ove page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: A 3.7 kb fragment of the upstream region of the mouse Dct gene drives expression a lacZ gene. Four founders expressing the transgene were generated. All lines show a similar pattern of expression. Transgene expression is detected in early retinal pigment epithelium (RPE), early neural crest cells, optic nerve, and neural crest-derived neuronal cells. This transgene can be used to study melanocyte development.
(J:134392)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:134392 Zhao S, et al., Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues. Dev Biol. 1999 Dec 1;216(1):154-63 |
| All: |
6 reference(s) |
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Analysis Tools
