Tbx21^tm2Srnr
Targeted Allele Detail

Summary

• Symbol: Tbx21^tm2Srnr
• Name: T-box 21; targeted mutation 2, Steven L Reiner
• MGI ID: MGI:5140531
• Gene: Tbx21 Location: Chr11:96988897-97006157 bp, - strand Genetic Position: Chr11, 60.95 cM, cytoband D
• Alliance: Tbx21^tm2Srnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137655
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 through 6 were flanked with loxP sites. (J:137655)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx21 Mutation: 39 strains or lines available

References

• Original: J:137655 Intlekofer AM, et al., Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science. 2008 Jul 18;321(5887):408-11
• All: 52 reference(s)