Tg(Lck-Il7r)1676Trma
Transgene Detail

Summary

• Symbol: Tg(Lck-Il7r)1676Trma
• Name: transgene insertion 1676, Thomas Malek
• MGI ID: MGI:5140599
• Synonyms: 7Ra^Tg, WT IL-7R
• Transgene: Tg(Lck-Il7r)1676Trma Location: unknown
• Alliance: Tg(Lck-Il7r)1676Trma page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Il7r)1676Trma expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il7r (MGI:96562)

• Mutation details: The transgene contains the mouse Il7r (interleukin-7 receptor) gene under the control of the proximal mouse Lck (lymphocyte protein tyrosine kinase) promoter. Line 1676 was generated. (J:66400)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:66400 Porter BO, et al., Control of T cell development In vivo by subdomains within the IL-7 receptor alpha-chain cytoplasmic tail. J Immunol. 2001 Jan 1;166(1):262-9
• All: 3 reference(s)