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Ccdc88atm2.1Mat
Targeted Allele Detail
Summary
Symbol: Ccdc88atm2.1Mat
Name: coiled coil domain containing 88A; targeted mutation 2.1, Masahide Takahashi
MGI ID: MGI:5140603
Synonyms: Girdin SA
Gene: Ccdc88a  Location: Chr11:29323658-29460808 bp, + strand  Genetic Position: Chr11, 16.61 cM
Alliance: Ccdc88atm2.1Mat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173379
Parent Cell Line:  CSL3 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation detailsExon 24 was replaced with a modified exon 24 in which nucleotide substitution(s) result in the amino acid substitution of alanine for serine at position 1417 (S1417A). A floxed neo cassette was inserted downstream of the modified exon 24 and removed by cre-mediated recombination. (J:173379)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccdc88a Mutation:  76 strains or lines available
References
Original:  J:173379 Wang Y, et al., Girdin Is an Intrinsic Regulator of Neuroblast Chain Migration in the Rostral Migratory Stream of the Postnatal Brain. J Neurosci. 2011 Jun 1;31(22):8109-8122
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory