Tg(I12b-cre/ERT2,-ALPP)37Fsh
Transgene Detail

Summary

• Symbol: Tg(I12b-cre/ERT2,-ALPP)37Fsh
• Name: transgene insertion 37, Gordon Fishell
• MGI ID: MGI:5140608
• Synonyms: Tg(Dlx1/2-cre/ERT2,-ALPP)37Fsh
• Transgene: Tg(I12b-cre/ERT2,-ALPP)37Fsh Location: unknown
• Alliance: Tg(I12b-cre/ERT2,-ALPP)37Fsh page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(I12b-cre/ERT2,-ALPP)37Fsh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	I12b (MGI:3833417)

• Mutation details: A targeting construct containing sequence encoding xre/ERT2 under the control of the mouse Dlx1/2, distal-less homeobox 1, distal-less homeobox 2, forebrain enhancer/ promoter, I12b, with an internal ribosomal entry sequence (IRES), followed by the human placental alkaline phosphatase gene (ALPP), and SV40 polyadenylation site sequence, was microinjected into FVB/N donor eggs. Founder line 37 was subsequently established. (J:134330)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	I12b (mouse) Summary of all recombinase alleles driven by I12b. Alliance mouse I12b gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:134330 Batista-Brito R, et al., The distinct temporal origins of olfactory bulb interneuron subtypes. J Neurosci. 2008 Apr 9;28(15):3966-75
• All: 7 reference(s)