Kcnn2^bc-8J
Spontaneous Allele Detail

Summary

• Symbol: Kcnn2^bc-8J
• Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; bouncy 8 Jackson
• MGI ID: MGI:5140705
• Gene: Kcnn2 Location: Chr18:45401927-45818950 bp, + strand Genetic Position: Chr18, 24.34 cM, cytoband C
• Alliance: Kcnn2^bc-8J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A point mutation at coding nucleotide 1159/1954/1984 of the cDNA (NM_080465/ENSMUST00000066890/NM_001312905) results in a valine to isoleucine substitution at position 387/652/662 of the encoded protein (NP_536713:p.V387I, ENSMUSP00000067884:p.V652I, NP_001299834:p.V662I). (J:222308)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnn2 Mutation: 43 strains or lines available

References

• Original: J:174667 Karst SY, et al., A remutation to bouncy on the C57BL/6J background, bouncy 8 Jackson. MGI Direct Data Submission. 2011
• All: 2 reference(s)