Vasn^tm1Zgl
Targeted Allele Detail

Summary

• Symbol: Vasn^tm1Zgl
• Name: vasorin; targeted mutation 1, Zhenggang Liu
• MGI ID: MGI:5140849
• Gene: Vasn Location: Chr16:4457805-4468666 bp, + strand Genetic Position: Chr16, 2.46 cM, cytoband A1
• Alliance: Vasn^tm1Zgl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173568
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• 495 bp (amino acids 287-452) of the coding region was replaced with a neo cassette. (J:173568)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vasn Mutation: 23 strains or lines available

References

• Original: J:173568 Choksi S, et al., A HIF-1 Target, ATIA, Protects Cells from Apoptosis by Modulating the Mitochondrial Thioredoxin, TRX2. Mol Cell. 2011 Jun 10;42(5):597-609
• All: 1 reference(s)