Pdgfrb^{tm12(Pdgfrb)Sor}
Targeted Allele Detail

Summary

• Symbol: Pdgfrb^{tm12(Pdgfrb)Sor}
• Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 12, Philippe Soriano
• MGI ID: MGI:5140889
• Synonyms: PDGFRbeta^(S)Wt
• Gene: Pdgfrb Location: Chr18:61178222-61218133 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pdgfrb^{tm12(Pdgfrb)Sor} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173602
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a splice acceptor, floxed neo/stop cassette, and the wild-type mouse cDNA. (J:173602)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdgfrb Mutation: 87 strains or lines available

References

• Original: J:173602 Olson LE, et al., PDGFRbeta Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development. Dev Cell. 2011 Jun 14;20(6):815-26
• All: 2 reference(s)