Cdc42^tm1.1Yizh
Targeted Allele Detail

Summary

• Symbol: Cdc42^tm1.1Yizh
• Name: cell division cycle 42; targeted mutation 1.1, Yi Zheng
• MGI ID: MGI:5140986
• Gene: Cdc42 Location: Chr4:137047011-137085007 bp, - strand Genetic Position: Chr4, 69.83 cM
• Alliance: Cdc42^tm1.1Yizh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174208
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 2. (J:174208)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdc42 Mutation: 45 strains or lines available

References

• Original: J:174208 Qian L, et al., Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27;193(7):1181-96
• All: 1 reference(s)