Ulk2^tm1.1Thsn
Targeted Allele Detail

Summary

• Symbol: Ulk2^tm1.1Thsn
• Name: unc-51 like kinase 2; targeted mutation 1.1, Craig B Thompson
• MGI ID: MGI:5141011
• Gene: Ulk2 Location: Chr11:61666475-61745899 bp, - strand Genetic Position: Chr11, 37.96 cM
• Alliance: Ulk2^tm1.1Thsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174297
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed exons 1 through 3 and the neo cassette. (J:174297)

Expression

In Mice Carrying this Mutation:

87 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ulk2 Mutation: 59 strains or lines available

References

• Original: J:174297 Cheong H, et al., Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11121-6
• All: 7 reference(s)