Neto2^tm1Mci
Targeted Allele Detail

Summary

• Symbol: Neto2^tm1Mci
• Name: neuropilin (NRP) and tolloid (TLL)-like 2; targeted mutation 1, Roderick R McInnes
• MGI ID: MGI:5141222
• Gene: Neto2 Location: Chr8:86363217-86427553 bp, - strand Genetic Position: Chr8, 41.61 cM, cytoband C4
• Alliance: Neto2^tm1Mci page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174557
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 - 6 were replaced with a neo cassette via homologous recombination. Immunoblot analysis of brain lysates from homozygous mice confirms the absence of protein expression. (J:174557)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Neto2 Mutation: 42 strains or lines available

References

• Original: J:174557 Tang M, et al., Neto1 Is an Auxiliary Subunit of Native Synaptic Kainate Receptors. J Neurosci. 2011 Jul 6;31(27):10009-10018
• All: 11 reference(s)