Zap70^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Zap70^m2Btlr
• Name: zeta-chain (TCR) associated protein kinase; mutation 2, Bruce Beutler
• MGI ID: MGI:5141315
• Synonyms: trebia
• Gene: Zap70 Location: Chr1:36800912-36821899 bp, + strand Genetic Position: Chr1, 15.41 cM, cytoband A4-C1
• Alliance: Zap70^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced A to T transversion at position 1566 (NCBI RefSeq: NM_009539). The mutation results in a tyrosine to phenylalanine substitution at amino acid 492 (Y492F). (J:174837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zap70 Mutation: 55 strains or lines available

References

• Original: J:174837 Beutler B, Direct Data Submission. MGI Direct Data Submission. 2011;v
• All: 1 reference(s)