Rtp1^tm1.1Hmat
Targeted Allele Detail

Summary

• Symbol: Rtp1^tm1.1Hmat
• Name: receptor transporter protein 1; targeted mutation 1.1, Hiroaki Matsunami
• MGI ID: MGI:5141446
• Gene: Rtp1 Location: Chr16:23247883-23252710 bp, + strand Genetic Position: Chr16, 14.21 cM
• Alliance: Rtp1^tm1.1Hmat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240532
• Parent Cell Line: EF1 (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace the coding region of the receptor transporter protein 1 (Rtp1) gene with a self-excising loxP-flanked cassette (itself containing a neomycin resistance (Neo) gene and a Cre recombinase gene). The allele lacks the neo cassette. (J:240532)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rtp1 Mutation: 22 strains or lines available

References

• Original: J:240532 Sharma R, et al., Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. Elife. 2017 Mar 06;6:e21895
• All: 3 reference(s)