Ascl1^tm2Fgu
Targeted Allele Detail

Summary

• Symbol: Ascl1^tm2Fgu
• Name: achaete-scute family bHLH transcription factor 1; targeted mutation 2, Francois Guillemot
• MGI ID: MGI:5141455
• Synonyms: Ascl1^flox, Ascl1^flx
• Gene: Ascl1 Location: Chr10:87326681-87329522 bp, - strand Genetic Position: Chr10, 43.64 cM
• Alliance: Ascl1^tm2Fgu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174732
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding sequence. A Venus gene with a 5' loxP site and an FRT-flanked neo cassette were inserted downstream of the 3' UTR. (J:174732)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ascl1 Mutation: 28 strains or lines available

References

• Original: J:174732 Pacary E, et al., Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron. 2011 Mar 24;69(6):1069-84
• All: 12 reference(s)